Could cross the 175 M$ barrier, final amount on Monday are often a little higher than first anticipated.
Also it doesn't take into account China and South Korea, two big markets where the film will open later. (271 m$ for Interstellar, probably not as much for Oppenheimer though: 51+23 for Dunkirk)
Lets say: 175*3+75 for China & Korea. We'd arrive at 600 million.
I can assure you that you would not be seeing these kind of numbers had any other director made Oppenheimer. Chris Nolan was the major reason people went to see this.